Healing & Tissue-Repair Peptides

N-acetyl-seryl-aspartyl-lysyl-proline — a naturally occurring anti-fibrotic tetrapeptide derived from the N-terminus of thymosin beta-4, regulated by ACE and studied for cardiac, renal, and pulmonary fibrosis.

A modified analog of BPC-157 incorporating alpha-aminoisobutyric acid (Aib) substitutions to enhance proteolytic stability and extend biological half-life while preserving cytoprotective activity.

A counter-regulatory heptapeptide of the renin-angiotensin system that opposes the vasoconstrictive and pro-inflammatory effects of angiotensin II through the Mas receptor, with cardioprotective, anti-fibrotic, and anti-inflammatory properties.

An endogenous peptide ligand for the APJ receptor (apelin receptor) with potent cardiovascular, angiogenic, and fluid homeostasis functions, studied as a potential therapeutic in heart failure and metabolic disease.

A 15-amino-acid peptide fragment derived from gastric juice protein BPC, studied extensively in animal models for tissue healing and gut integrity.

A 21-amino-acid endogenous peptide derived from chromogranin A that inhibits catecholamine release via nicotinic acetylcholine receptor antagonism, with cardiovascular protective, antimicrobial, and metabolic regulatory properties under active investigation for hypertension and heart failure.

A synthetic octapeptide tight junction regulator studied in Phase III clinical trials for celiac disease — acts locally in the gut to prevent paracellular permeability increase (leaky gut).

A polyethylene glycol-conjugated variant of BPC-157 engineered for extended half-life and reduced injection frequency while retaining the parent peptide's tissue-healing properties.

Synthetic fragment of Thymosin β4 investigated for actin-binding, cell migration, and tissue repair across muscle, cornea, and cardiac models.

A 43-amino acid peptide and the primary intracellular G-actin sequestering protein. TB-500 is a synthetic fragment of Thymosin Beta-4's active site — this is the full-length parent molecule with broader tissue repair and anti-inflammatory evidence.