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Epitalon
Longevity / Bioregulator

Epitalon

Research-Grade

Epitalon is a synthetic tetrapeptide designed by Russian gerontologist Vladimir Khavinson based on work with the pineal-gland extract Epithalamin. A long-running line of Eastern European research has examined Epitalon in rodent and human cohort studies, reporting effects on telomerase expression, melatonin restoration, circadian rhythm, and all-cause mortality in multi-year institutional cohorts. Most of this evidence exists outside mainstream Western peer-review channels and interpretation remains contested. Epitalon is typically administered as short subcutaneous courses (10 days) repeated 2–3 times per year in published Russian protocols. It is classified as a research peptide globally and is widely used off-label in longevity practice despite the contested evidence base.

Specifications

Origin / ManufacturerSynthetic
Active Components
Epitalon (Ala-Glu-Asp-Gly)
StorageLyophilized room-temp; reconstituted 2–8°C
Form FactorLyophilized powder vial

Sources & References

Every clinical claim on this page traces to a primary peer-reviewed source.

  1. 1Khavinson VK, Bondarev IE, Butyugov AA. Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells. Bulletin of Experimental Biology and Medicine. 2003;135(6):590-2. doi:10.1023/a:1025493705728 PMID:12937682
  2. 2Anisimov VN, Khavinson VKh. Peptide bioregulation of aging: results and prospects. Biogerontology. 2010;11(2):139-49. doi:10.1007/s10522-009-9249-8 PMID:19830585

Reviewed by

Clinical Research Review Board

Pharmacology & Endocrinology Review

All clinical claims cross-checked against primary sources. Read our editorial policy →

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Reviewed by Clinical Research Review BoardPharmacology & Endocrinology Review

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