Cosmetic Peptides

A biomimetic signaling peptide and key active ingredient in Capixyl hair loss treatments, proposed to counteract DHT-driven follicle miniaturization and reduce perifollicular inflammation.

A next-generation biomimetic lipopeptide from Sederma's Matrixyl family that targets age-related dermal matrix architecture changes by upregulating TGF-beta signaling, fibrillin-1, and elastic fiber network components — addressing deep structural skin aging beyond collagen alone.

A biotinylated derivative of the copper-binding tripeptide GHK, combining the collagen-stimulating and wound-healing properties of GHK-Cu with biotin's keratin-supporting activity for enhanced hair and nail applications.

A copper-binding tripeptide (Ala-His-Lys-Cu) studied for hair follicle stimulation, dermal papilla cell proliferation, and VEGF upregulation in hair growth applications.

A naturally occurring copper-binding tripeptide (Gly-His-Lys) with decades of cosmetic dermatology research in wound healing and skin remodeling.

The base copper-binding tripeptide (Gly-His-Lys) found in human plasma and tissues — a precursor to GHK-Cu with intrinsic bioactivity in wound healing, gene modulation, and anti-inflammatory signaling.

A copper-binding tripeptide (Lys-His-Lys) that chelates Cu2+ ions to promote collagen synthesis, wound healing, and hair follicle stimulation as an alternative to GHK-Cu.

A lipidated derivative of the copper-binding tripeptide GHK, designed for enhanced skin penetration in topical anti-aging formulations.

An anti-inflammatory lipopeptide that suppresses IL-6 and TNF-α release in skin — used in cosmetic formulations targeting redness, irritation, and sensitivity in rosacea-prone and reactive skin types.

A lipopeptide modeled on the elastin repeat sequence VGVAPG — stimulates elastin production in dermal fibroblasts via the 67-kDa elastin-binding protein receptor, targeting skin elasticity loss rather than collagen depletion.

The original Matrixyl peptide — a lipopeptide that mimics the collagen I pro-peptide fragment to stimulate fibroblast production of collagens I, III, IV, fibronectin, and hyaluronic acid. One of the most studied anti-wrinkle cosmetic peptides.

A lipopeptide that suppresses IL-6 and glycation-driven inflammation in skin, often combined with Palmitoyl Oligopeptide in anti-aging formulations (Matrixyl 3000).

A lipopeptide signal peptide (INCI: Palmitoyl Tripeptide-1) used in Matrixyl and advanced skincare formulations to stimulate collagen I, III, and fibronectin synthesis via TGF-β activation.

A lipopeptide TGF-β mimetic that stimulates collagen I and III synthesis in dermal fibroblasts — used in anti-wrinkle formulations as a signaling peptide rather than a neuromuscular inhibitor.

A pentapeptide modeled on the SNAP-25 SNARE protein that modulates neuromuscular junction signaling — marketed as a complementary alternative to Argireline for expression-line reduction in anti-wrinkle formulations.