Peptides Academy
NA-Selank Amidate
Research-Grade
NA-Selank Amidate is a modified version of the Russian-developed anxiolytic peptide Selank (Thr-Lys-Pro-Arg-Pro-Gly-Pro, itself derived from the endogenous tetrapeptide tuftsin). The N-acetylation and C-terminal amidation modifications protect the peptide from aminopeptidase and carboxypeptidase degradation, respectively, extending its half-life and improving CNS penetration via intranasal delivery. The parent compound Selank has been approved in Russia as an anxiolytic since 2009 and has documented effects on GABA receptor modulation, brain-derived neurotrophic factor (BDNF) expression, and serotonin metabolism. NA-Selank Amidate is positioned as a research-grade enhancement designed for greater stability and potency per dose, though its clinical evidence base is thinner than that of standard Selank.
Specifications
| Origin / Manufacturer | Synthetic (tuftsin derivative, modified) |
| Active Components | N-Acetyl Selank Amidate |
| Storage | Lyophilized room-temp; reconstituted 2–8°C |
| Shelf Life | Lyophilized 24+ months; reconstituted 21 days refrigerated |
| Form Factor | Lyophilized powder or nasal spray |
Frequently Asked Questions
Sources & References
Every clinical claim on this page traces to a primary peer-reviewed source.
- 1Zozulya AA, Gabaeva MV, Sokolov OY, et al.. Personality, coping style, and humoral immunity. International Immunopharmacology. 2008;8(8):1146-52. PMID:18550016
- 2Semenova TP, Kozlovskii II, Zuikov AV. Effects of Selank on cognitive processes after damage to the catecholamine system of the brain. Eksperimental'naya i Klinicheskaya Farmakologiya. 2007;70(4):5-8.
Reviewed by
Clinical Research Review Board
Neuropharmacology Review
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