Is Protini worth $68?

Depends on what you're buying. If you want a single-step peptide moisturizer with a luxurious feel, yes. If you care mainly about peptide concentration per dollar, a layered routine of The Ordinary Buffet + a basic moisturizer gives equivalent peptide exposure at $35.

Can I use Protini with retinol?

Yes — Drunk Elephant designed it as a retinoid-compatible step. Apply retinol first, let absorb, then Protini on top.

cream50ml

Protini Polypeptide Cream

Name: Protini Polypeptide Cream
Brand: Drunk Elephant
Price: 68 USD
Availability: InStock

Drunk Elephant

Protini is Drunk Elephant's flagship peptide moisturizer — a full-coverage cream built around a signal peptide complex (including copper tripeptide-1, palmitoyl pentapeptide-4, and Tripeptide-1) layered with amino acids and plant extracts. Unlike booster serums that need to layer under something, Protini is engineered as a complete moisturizer — skin feel, occlusion, and peptide load in one step. The price point is significant ($68 for 50ml) and the positioning is premium, but the mechanism is comparable to multi-peptide serums at a fraction of the cost. The decision is more about texture preference and brand affinity than peptide science.

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Peptides in this product

GHK-Cu (Copper Tripeptide-1)

Collagen synthesis

Argireline (Acetyl Hexapeptide-8)

Expression-line softening

Targets

Peptides for Anti-Aging Peptides for Skin & Glow

Key ingredients

Copper Tripeptide-1Palmitoyl Pentapeptide-4Tripeptide-1Pygmy Waterlily ExtractAmino Acid Complex

How to use

Apply a small amount to face and neck AM and PM after serums. Pairs well with retinoids in the PM routine and vitamin C in the AM (the peptide list here doesn't contain free copper-tripeptide, so layering with ascorbic acid is safe).