Peptides AcademySleep & Circadian Peptides
Peptides with proposed effects on sleep architecture or circadian regulation. DSIP (delta sleep-inducing peptide) is the historical flagship; modern evidence is sparse.
Sleep Peptides (2)
Cortistatin
Research-Grade
A neuropeptide structurally related to somatostatin that promotes slow-wave sleep, modulates cortical activity, and exerts potent anti-inflammatory effects through both somatostatin-shared and cortistatin-specific receptor pathways.
DSIP (Delta Sleep-Inducing Peptide)
Research-Grade
A nonapeptide first studied in rabbits in the 1970s for its effect on delta-wave sleep. Small 1980s-1990s human trials gave mixed results; in the US it is a research-only compound.